Synthesis and Antioxidant activities of pyrido[1,2-a] pyrimidine derivatives
Chemistry
संकेत शब्द:
DMF, Pyrido pyrimidine, Bis (methylthio) methylene malononitrileसार
The bis (methylthio) methylene malononitrile (1) on treatment with 2-amino-5-bromo pyridine (2) in N,N-dimethyl formamide (DMF) and anhydrous potassium carbonate, gives7-bromo 3-cyano-4-imino-2-(methylthio)-4H-pyrido[1,2-a]pyrimidine (3). This pyrimidine derivative then further reacted with nucleophiles different substituted aromatic amines and Phenols.
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